APPLICATION
|
LIPIDOMIC DELIVERABLE
|
| Mechanism of action |
Elucidation of the changes in molecular lipids and lipid biochemical pathways responsive to the test condition or compound |
| Dose Response |
Quantification of the dose responsive lipids |
| Toxicological studies |
Correlation of lipid changes to toxicology, for example, monitor plasma membrane leakage |
| Target validation |
Identification of the target responsive to the test compound by quantifiable changes in molecular lipids and biochemical pathways |
| Target discovery |
Identification of causal lipids in particular disease areas, identification of the druggable target |
| Compound selection |
Lipidomic studies to gauge efficacy and off-target effects |
| Drug compound quantification |
Quantification of the drug compound of interest in any chosen tissue or biofluid and correlation to lipid and other data |
| Translational studies |
Lipidomic studies and their translation across various test species |